Synthetic Pentadecapeptide BPC-157 comprises a 15 amino acid chain. In fact, it is a typically partial sequence of the Body Protection Compound. The BPC, with a molecular weight of 1,419, was discovered and isolated from the gastric juice of humans.
This peptide is considered synthetic because it doesn’t share the homology with any significant natural peptides. Besides, it is way more stable in comparison to all other peptides. It also has the capability of withstanding stomach acid degradation in plasma for a minimum of 24 hours.
BPC-157 – Action Mechanism
The synthetic peptide has been used in animal trials and has been tested for its cytoprotective properties. It has also been considered for wound healing activities along with other significant effects. But until today, the exact mechanism is not clearly understood.
Studies suggest that the effect of BPC-157 typically comes from its capability of upregulating growth factors. However, the peptide also has the potential to modulate Nitric Oxide synthesis, increasing angiogenesis, affecting bone morphogenic proteins, etc.
What are the Effects of Synthetic Pentadecapeptide BPC-157?
Until today, numerous studies and research have been conducted with this synthetic peptide and have revealed several beneficial effects. Here, we have made a comprehensive listing of a few effects:
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Tendon Fibroblast
An experiment with a damaged Achilles tendon revealed that BPC-157 could deliberately increase the production of fibroblast. Besides, it also increases the reformation of collagen, which typically exceeds the platelet-growth factor within the first four days. The peptide can also increase the survivability of the tendon fibroblasts, which are subjected to oxidative stress.
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Angiogenesis
Angiogenesis is primarily one core process of healing wounds and growing tissues. And BPC-157 has revealed its capability of increasing Angiogenesis with the help of CAM assay. Another study revealed that this peptide could typically increase the expression of Vascular Endothelial Growth Factor 2.
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Neurotransmission
Even though BPC-157 has zero binding capacity to neuro receptors, it has revealed its involvement in the specific serotonergic system. This is primarily because of its effect on the gastric system. After the peptide is administered, it can significantly increase serotonin production in the regions of the brain.
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Gastroprotective
BPC-157 can deliberately prevent gastric ulcers and is administered with agents that can induce stomach ulcers. Besides, it is immensely beneficial for intestinal inflammation in comparison to ranitidine and omeprazole.
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Parkinson’s and Multiple Sclerosis
In a study, BPC-157 has deliberately exhibited less brain damage in test subjects with Parkinson’s disease. And it appears that this peptide can lessen the damage promoted by MPTP.
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Antidepressant
In an experimental study, BPC-157 revealed a remarkable antidepressant effect. Most importantly, this effect is much more prominent than nialamide and imipramine.
To Conclude
If you are looking forward to conducting certain clinical research with BPC-157, then you must get them from Loti Labs. These USA-made peptides will seamlessly ensure the integrity of your research. Besides, these synthetic peptides have been tested through HPLC and Mass spectrometry only to ensure quality. You will find them in lyophilized powder form and are sold in 5mh vials.
